Ipamorelin: A Selective Growth Hormone Secretagogue

Ipamorelin is a synthetic pentapeptide that functions as a selective growth hormone secretagogue (GHS). It mimics ghrelin, a natural hormone that stimulates growth hormone (GH) release from the pituitary gland.

Research shows that Ipamorelin selectively increases GH levels without significantly affecting cortisol or prolactin levels, making it a promising candidate for muscle growth, fat reduction, and anti-aging applications. Unlike older GHS peptides, Ipamorelin exhibits minimal side effects, such as reduced risk of excessive hunger and elevated stress hormones.

Preclinical studies suggest that Ipamorelin may enhance muscle recovery, improve bone density, and support metabolic health. Its ability to stimulate natural GH production has drawn interest for potential therapeutic applications in age-related muscle loss and recovery from injuries.

Although Ipamorelin appears to have a favorable safety profile, more clinical trials are necessary to confirm its long-term efficacy and safety.